MAPKAP Kinase 2 anticorps (pSer272) (FITC)

N° du produit ABIN710538

Cet anticorps anti-MAPKAP Kinase 2 est un anticorps Lapin Polyclonal détectant MAPKAP Kinase 2 dans IF (p). Adapté pour Humain, Souris, Rat, Boeuf (Vache), Poulet et Porc.

Aperçu rapide pour MAPKAP Kinase 2 anticorps (pSer272) (FITC) (ABIN710538)

Antigène: MAPKAP Kinase 2 (MAPKAPK2) (Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 (MAPKAPK2))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Poulet, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAPKAP Kinase 2 est conjugé à/à la FITC

Application: Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-MAPKAP Kinase 2 anticorps (FITC)

Épitope: pSer272

Specificité: Excitation / Emission Wavelengths: 495nm/519nm

Réactivité croisée: Rat (Rattus), Poulet, Porc, Boeuf (Vache)

Purification: purified by Protein A

Immunogène: KLH conjugated synthetic phosphopeptide derived from human MAPKAPK2 around the phosphorylation site of pSer272

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P)(1:100-500)
Optimal working dilution should be determined by the investigator.

Commentaires:

Excitation / Emission wavelength: 494nm / 518nm

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 µg/µL

Buffer: Aqueous buffered solution containing 100 µg/mL BSA, 50 % glycerol and 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 4 °C for 12 months

Date de péremption: 12 months

Détails sur MAPKAP Kinase 2

Antigène: MAPKAP Kinase 2 (MAPKAPK2) (Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 (MAPKAPK2))

Autre désignation: MAPKAPK2

Sujet: MAP kinase activated protein kinase 2 (MAPKAP Kinase 2), also known as p45 hsp27 kinase, is a 45-54 kDa serine/threonine protein kinase that contains a proline rich sequence and two putative SH3 binding sites. MAPKAP Kinase 2 is activated in response to stress, IL1 and TNF, possibly catalyzed by p38/Hog dependent phosphorylation. One of the major substrates of MAPKAP Kinase 2 is hsp27, which stimulates actin polymerization in order to facilitate recovery from destruction of cytoskeleton during cellular stresses. MAPKAP2 is implicated in several disorders including ischemic brain injury and heart failure and has been shown to be important in regulating stress resistance and the production of TNF alpha.

Poids moléculaire: 44kDa

ID gène: 9261

Pathways: Signalisation MAPK, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades